Dr. Mario Online Rx

Dr. Mario Online Rx
System Wii (WiiWare)
Developer Nintendo, Intelligent Systems
Genre Puzzle
Series Super Mario Series

A launch title for the WiiWare download content service in Japan and Europe. Clear the bottles of viruses by lining up the pills Mario throws, creating lines of four of the same colour.

Dr. Mario Online Rx introduces two new elements to the series: online multiplayer mode and the Virus Buster game.

Release Information

Region Name Release
Japan ドクターマリオ & 細菌撲滅 Dr. Mario & Saikin Bokumetsu 25 Mar 2008
Europe Dr. Mario & Germ Buster 20 May 2008
US Dr. Mario Online Rx 26 May 2008

Game Modes

Dr. Mario

The main game plays exactly the same as previous entries in the series. The only changes are the updated 3D graphics and the ability to see the next three pills that will be dropped into the jar. The two music tracks introduced in Dr. Mario 64 have also been renamed from "Cube" and "Que Que" to "Cough" and "Sneeze".

Online Multiplayer

Dr. Mario Online Rx multiplayer mode is for two players only, but it can be played online through the Nintendo Wi-Fi network. You are also given the option to play with Dr. Mario or as one of the Mii characters saved to the Wii.

Virus Buster

Between one and four players can take part. Using the Wii Remote, players have to pull Megavitamins into place to clear the viruses on the screen. You can set the virus level and music for this mode.

Virus Buster is based on a minigame originally from Brain Age 2 on the Nintendo DS.